Recent Research Topics

Topic 1: Single Polymer Chain upon Stretching: Physical Models vs Experimental Results

Modeling Single Chain Elasticity of Single-stranded DNA: a Comparison of Three Models.
Polymer
, 2009, 50, 930-935. [Link] [Database]

Inherent Stretching Elasticity of a Single Polymer Chain with a Carbon-Carbon Backbone.
Langmuir
, 2013, 29, 4315¨C4319. [Link]

How Big Is Big Enough? Effect of Length and Shape of Side Chains on the Single-Chain Enthalpic Elasticity of a Macromolecule.
Macromolecule
, 2016, 49, 3559−3565. [Link]

The unexpected flexibility of natural cellulose at a single-chain level and its implications to the design of nano materials.
Nanoscale, 2014, 6, 13421-13424. [Link]

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Topic 2: The Impact of Water on the Single-chain Mechanics of Biomacromolecules

Weakly bound water molecules shorten single-stranded DNA.
J. Am. Chem. Soc. 2006, 128, 6636-6639. [Link]

Effects of Water on the Single-Chain Elasticity of Poly(U) RNA.
Langmuir 2015, 31, 6107-6113. [Link]

Double Stranded DNA Dissociates into Single Strands when Dragged into a Poor Solvent.
J. Am. Chem. Soc., 2007, 129, 14710-14716. [Link]

Protein denaturation at a single-molecule level: the effect of nonpolar environments and its implications on the unfolding mechanism by proteases.
Nanoscale, 2015, 7, 2970-2977. [Link]

Effects of Water Content of the Mixed Solvent on the Single- Molecule Mechanics of Amylose.
ACS Macro Lett., 2018, 7, 672-676. [Link]

The Possible Roles of Water in the Prebiotic Chemical Evolution of DNA.
Phys. Chem. Chem. Phys.
2010, 12, 10147-10153. [Link]

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Topic 3: Single-chain Mechanics of Environmental Responsive Polymers

Unexpected Temperature-Dependent Single Chain Mechanics of Poly(N-isopropyl-acrylamide) in Water.
Langmuir
, 2012, 28, 5151-5157. [Link]

Single-Chain Mechanics of Poly(N,N-diethylacrylamide) and Poly(N-isopropylacrylamide): Comparative Study Reveals the Effect of Hydrogen Bond Donors.
Langmuir
, 2013, 29, 12176¨C12182. [Link]

Single-chain mechanics of poly(N-isopropyl-acrylamide) in the water/methanol mixed solvent.
Polymer, 2013, 54, 3737-3743. [Link]

Effect of size of solvent molecule on the single-chain mechanics of poly(ethylene glycol): implications on a novel design of molecular motor.
Nanoscale, 2016, 8, 17820¨C17827. [Link]

Contact: Prof. Dr. Shuxun Cui, Northeastern University
E-mail: cuishuxun(at)neu.edu.cn